COA Anatomy

How to read a peptide COA

A field-by-field walkthrough of a real Certificate of Analysis — product and sequence, lot number, dates, purity, identity, water, endotoxin, storage — and the red flag hiding in each field.

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Analytical Methods

HPLC vs LC-MS: what each proves

HPLC quantifies purity; LC-MS confirms identity. Why you need both, how to read a chromatogram, and why 98% purity means nothing if it is 98% of the wrong molecule.

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Verification

Spotting a faked COA

Nine concrete red flags of faked, recycled, and vendor-issued certificates — from missing lot numbers to impossible purity values — with how to verify each one.

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Lab Accreditation

What ISO/IEC 17025 accreditation means

Accreditation versus certification, what an accreditation number is, and why a vendor's in-house QC is not the same as an independent, accredited laboratory.

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Hidden Fields

Karl Fischer, endotoxin & hidden fields

Water content by Karl Fischer, endotoxin by LAL, residual solvents and counter-ions — the fields most certificates omit, and why their absence leaves the picture incomplete.

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